Sulfometuron methyl

Sulfometuron methyl is an organic compound used as an herbicide.^[1] It is classed as a sulfonylurea. It functions via the inhibition of the enzyme acetolactate synthase, which catalyzes the first step in biosynthesis of the branched-chain amino acids valine, leucine, and isoleucine.^[2]

Sulfometuron methyl

Names
Preferred IUPAC name Methyl 2-{[(4,6-dimethylpyrimidin-2-yl)carbamoyl]sulfamoyl}benzoate
Identifiers
CAS Number	74222-97-2 Y
ChEBI	CHEBI:9348
ECHA InfoCard	100.070.688
EC Number	277-780-6
PubChem CID	52997
UNII	JLY5D60J1A Y
CompTox Dashboard (EPA)	DTXSID0034936
Properties
Chemical formula	C15H16N4O5S
Molar mass	364.38 g·mol−1
Appearance	White solid
Density	1.48 g/cm3
Melting point	202 °C (396 °F; 475 K)
Solubility in water	244 mg/L
Acidity (pKa)	5.2
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

References

1. "Sulfometuron-methyl". Extension Toxicology Network. Retrieved 10 February 2016.
2. LaRossa, Robert; Schloss, John (1984). "The Sulfonylurea Herbicide Sulfometuron Methyl Is an Extremely Potent and Selective Inhibitor of Acetolactate Synthase in Salmonella typhimurium". Journal of Biological Chemistry. 259 (14): 8753–8757. doi:10.1016/S0021-9258(17)47217-6. PMID 6378902.