Sequoia, Sequoya or Sequoyah refers to a type of tree in the cypress family which includes the redwood trees. By extension the name may refer to:
Other science and technology
United States
- State of Sequoyah, an attempt in the early 20th century by Native Americans to form their own state
- Canyon, California, formerly Sequoya
- Mount Sequoyah, Great Smoky Mountains
- Sequoia Hall, home of the Statistics Department of Stanford University
- Sequoia Hospital, Redwood City, California
- Sequoia National Park, a national park in the southern Sierra Nevada, California
- Sequoia Park Zoo, in Eureka, California
- Sequoyah County, Oklahoma, a county in mid-eastern Oklahoma bordering Arkansas
- Sequoyah Nuclear Plant, Tennessee
- Sequoyah, Oklahoma, an unincorporated community in northeastern Oklahoma
- Sequoia Middle School (disambiguation), several schools
- Sequoia High School (disambiguation), several schools
- Sequoyah High School (Georgia), public school in Canton, Georgia
- Sequoyah High School (Claremore, Oklahoma), public school
- Sequoyah High School (Tahlequah, Oklahoma), high school and Native American boarding school
- Sequoyah School, a non-profit, independent alternative school in Pasadena, California
- Sequoia University, a defunct Los Angeles diploma mill
- Piper Sequoya, a variant of the Piper Aerostar, a light twin-engine utility aircraft
- Sequoia Falco, a light, acrobatic aircraft
- Sequoia Field Airport, near Visalia, California, US
- Toyota Sequoia, a sport utility vehicle
- USS Sequoia, several US Navy ships
- USS Sequoyah (SP-426), a patrol boat in commission from 1917 to 1919
- Sequoyah (1767–1843), American Indian silversmith and inventor of the Cherokee syllabary
- Johnny Sequoyah (born 2002), American actress
- Sequoia Holmes, American basketball player
- Sequoia Nagamatsu, American writer and professor
- Billy Ray Waldon, also known as Nvwtohiyada Idehesdi Sequoyah (born 1952), American former fugitive, American Indian Movement activist, and Esperantist