Transcription initiation protein SPT3 homolog

Transcription initiation protein SPT3 homolog is a protein that in humans is encoded by the SUPT3H gene.^[5][6][7]

SUPT3H
Identifiers
Aliases	SUPT3H, SPT3, SPT3L, SPT3 homolog, SAGA and STAGA complex component
External IDs	OMIM: 602947; MGI: 1923723; HomoloGene: 121570; GeneCards: SUPT3H; OMA:SUPT3H - orthologs
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6p21.1 Start 44,809,317 bp[1] End 45,377,953 bp[1]
Gene location (Mouse) Chr. Chromosome 17 (mouse)[2] Band 17|17 B3 Start 45,088,039 bp[2] End 45,430,177 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gonad sperm testicle oocyte left testis sural nerve right testis cartilage tissue ventricular zone left ovary Top expressed in hand interventricular septum muscle of thigh primary oocyte zygote seminiferous tubule spermatid otolith organ granulocyte utricle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein heterodimerization activity histone acetyltransferase activity transcription coactivator activity DNA binding transcription coregulator activity Cellular component transcription factor TFTC complex nucleus nucleoplasm SAGA complex transcription factor TFIID complex Biological process regulation of transcription by RNA polymerase II positive regulation of transcription, DNA-templated histone deubiquitination regulation of transcription, DNA-templated transcription by RNA polymerase II histone H3 acetylation transcription, DNA-templated Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 8464 109115 Ensembl ENSG00000196284 ENSMUSG00000038954 UniProt O75486 n/a RefSeq (mRNA) NM_001261823 NM_003599 NM_181356 NM_001350324 NM_001350325 NM_001350326 NM_001350327 NM_001350329 NM_178652 NM_001357320 RefSeq (protein) NP_001248752 NP_003590 NP_852001 NP_001337253 NP_001337254 NP_001337255 NP_001337256 NP_001337258 n/a Location (UCSC) Chr 6: 44.81 – 45.38 Mb Chr 17: 45.09 – 45.43 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Interactions

Transcription initiation protein SPT3 homolog has been shown to interact with GCN5L2,^[8][9] TAF6L,^[9] TADA3L,^[9] TAF5L,^[9] SF3B3,^[9] SUPT7L,^[9] Myc,^[10] TAF9,^[9] Transformation/transcription domain-associated protein,^[9] TAF12,^[9] TAF10,^[8][9] TAF4^[8] and DDB1.^[9]