Profen (drug class)

The profens are a class of nonsteroidal anti-inflammatory drugs.^[1] Profens are also known as 2-arylpropionic acids to reflect their chemical structure.^[2] The most common example of a profen is ibuprofen, which has been sold under the brand name Profen among others.

Left: general chemical structure of profens (Ar = aryl group). Right: chemical structure of ibuprofen

Other drugs in the class include:

• Alminoprofen
• Benoxaprofen
• Carprofen
• Dexibuprofen
• Dexketoprofen
• Fenoprofen
• Flunoxaprofen
• Flurbiprofen
• Indoprofen
• Ketoprofen
• Loxoprofen
• Miroprofen
• Naproxen
• Pelubiprofen
• Pirprofen
• Pranoprofen
• Suprofen
• Tarenflurbil
• Tiaprofenic acid
• Vedaprofen
• Zaltoprofen

References

1. Evans, A. M. (1996). "Pharmacodynamics and pharmacokinetics of the profens: Enantioselectivity, clinical implications, and special reference to S(+)-ibuprofen". Journal of Clinical Pharmacology. 36 (12 Suppl): 7S–15S. doi:10.1002/j.1552-4604.1996.tb00003.x. PMID 9013378. S2CID 26944804.
2. Landoni, M.; Soraci, A. (2001). "Pharmacology of Chiral Compounds 2-Arylpropionic Acid Derivatives". Current Drug Metabolism. 2: 37–51. doi:10.2174/1389200013338810. PMID 11465150.