Pivhydrazine

Pivhydrazine (trade name Tersavid), also known as pivalylbenzhydrazine and pivazide, is an irreversible and non-selective monoamine oxidase inhibitor (MAOI) of the hydrazine family. It was formerly used as an antidepressant in the 1960s, but has since been discontinued.^[1][2][3]

Pivhydrazine

Clinical data
Other names	Angorvid, Betamezid, Neomarsilid, Pivazide, Pivhydrazine
Routes of administration	Oral
ATC code	none
Legal status
Legal status	In general: ℞ (Prescription only)
Identifiers
IUPAC name N'-benzyl-2,2-dimethyl-propanehydrazide
CAS Number	306-19-4 Y
PubChem CID	9375
ChemSpider	9007 Y
UNII	TK1T520ASG
ChEMBL	ChEMBL2106941
CompTox Dashboard (EPA)	DTXSID50184667
ECHA InfoCard	100.005.620
Chemical and physical data
Formula	C12H18N2O
Molar mass	206.289 g·mol−1
InChI InChI=1S/C12H18N2O/c1-12(2,3)11(15)14-13-9-10-7-5-4-6-8-10/h4-8,13H,9H2,1-3H3,(H,14,15) Y Key:FWWDFDMCZLOXQI-UHFFFAOYSA-N Y
(verify)

See also

• Hydrazine (antidepressant)

References

1. Herman ZS, Sokola A, Lenartowicz H, Zieliński M, Depta L (May–June 1976). "The influence of antidepressive drugs on the level of acetylcholine and on the acetylcholinesterase activity in the brain of rats". Polish Journal of Pharmacology and Pharmacy. 28 (4): 313–21. OCLC 1586290. PMID 981020.
2. Bolton GC, Griffiths LA (November–December 1979). "The metabolic disposition of [14C]pivhydrazine, [14C]mebanazine, and [14C]benzylhydrazine in the rat". Drug Metabolism and Disposition. 7 (6): 388–92. OCLC 1784380. PMID 43225.
3. Mikhaĭlova TV, Gilev AP, Khavronina-Gureeva ZP (1969). "[Central effects of betamezide]". Farmakologiia i Toksikologiia (in Russian). 32 (6): 652–6. OCLC 1568906. PMID 5381593.