Pandora's box refers to the container opened by the Greek mythological woman Pandora releasing all the evils of humanity into the world.
Pandora's box may also refer to:
- Pandora's Box (play), a 1904 German play (Die Büchse der Pandora) by Frank Wedekind
- Pandora's Box (1929 film), a film by G. W. Pabst, starring Louise Brooks
- Pandora's Box (2008 film), a Turkish drama directed by Yeşim Ustaoğlu
- Pandora's Box (2017 film), a sci-fi television film starring Corin Nemec; originally titled Doomsday Device
- Trois 2: Pandora's Box, a 2002 erotic thriller directed by Rob Hardy
- Pandora's Box (British TV series), a 1992 documentary series by Adam Curtis
- Pandora's Box (Chinese TV series), a 2021 mystery series
- "Pandora's Box", two-episodes story of the Mighty Max cartoon TV series
- "Pandora's Box", a 2000 episode of the CBS series Touched by an Angel (season 6), the box used as a metaphor for the Internet.
Plot devices in other works
- Pandora's Box (band), a 1980s American female pop group created by Jim Steinman
- Pandora's Box (album), by Aerosmith, 1991
- "Pandora's Box" (Aerosmith song), 1974
- "Pandora's Box" (Orchestral Manoeuvres in the Dark song), 1991
- "Pandora's Box", a song by Donna Summer from Love to Love You Baby, 1975
- "Pandora's Box", a song by Edguy from Age of the Joker, 2011
- "Pandora's Box", a song by NCT 127 from Neo Zone, 2020
- "Pandora's Box", a song by Nonpoint from Nonpoint, 2012
- "Pandora's Box", a song by Procol Harum from Procol's Ninth, 1975
- "Pandora's Box", a song by MARINA from Ancient Dreams in a Modern Land, 2021
- "Pandora's Box", a song by J-Hope from Jack in the Box, 2022