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Combination drug From Wikipedia, the free encyclopedia
Olanzapine/samidorphan, sold under the brand name Lybalvi, is a fixed-dose combination medication for the treatment of schizophrenia and bipolar I disorder.[1] It contains olanzapine, an atypical antipsychotic, and samidorphan, an opioid antagonist.[1][2][3] Samidorphan reduces the weight gain associated with olanzapine while still allowing olanzapine to exert its therapeutic effect.[4][5] The formulation was approved for medical use in the United States in May 2021.[1][6]
Combination of | |
---|---|
Olanzapine | Atypical antipsychotic |
Samidorphan | Opioid antagonist |
Clinical data | |
Trade names | Lybalvi |
Other names | ALKS-3831; OLZ/SAM |
AHFS/Drugs.com | Micromedex Detailed Consumer Information |
MedlinePlus | a621051 |
License data | |
Routes of administration | By mouth |
ATC code | |
Legal status | |
Legal status | |
Identifiers | |
KEGG |
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