Norepinephrine–dopamine releasing agent
Drug class From Wikipedia, the free encyclopedia
A norepinephrine–dopamine releasing agent (NDRA) is a type of drug which induces the release of norepinephrine (and epinephrine) and dopamine in the body and/or brain.[1][2][3][4][5]
 | It has been suggested that this article be merged with Amphetamine type stimulant. Reason: They are almost exactly the same thing. (Discuss) Proposed since November 2024. |
Examples of NDRAs include phenethylamine, tyramine, amphetamine, dextroamphetamine, levoamphetamine, methamphetamine, lisdexamfetamine, 4-fluoroamphetamine, cathine, cathinone, methcathinone, phentermine, phenmetrazine, aminorex, and benzylpiperazine.[1][2][5][3]
NDRAs have psychostimulant effects and are used to treat medical conditions like attention-deficit hyperactivity disorder (ADHD), binge eating disorder, obesity, narcolepsy, and for other indications.[3][1][2] They are also used to increase motivation[6][7] and to enhance performance.[8][9][10]
A closely related type of drug is a norepinephrine–dopamine reuptake inhibitor (NDRI), for instance bupropion, methylphenidate, and nomifensine.[11][12]
Mechanism of action
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