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Nikola Panayot Pavletich is the former chair of structural biology at Memorial Sloan Kettering Cancer Center.[1]
Pavletich received his BS in chemistry from Caltech in 1988 and his PhD in molecular biology and genetics from Johns Hopkins University School of Medicine in 1991.[2] He did a postdoc at MIT with Carl Pabo.
He joined the faculty at Sloan Kettering in 1993 and was named chair of the Structural Biology Program in 2003.[3] He has been an HHMI investigator since 1997.
His laboratory researches malignant cell growth and DNA damage contributing to the development of cancer. DNA damage repair is a significant factor in whether a cell will become cancerous after genetic insult. Some of his major focuses have been the mTOR pathway and BRCA1. His lab uses x-ray crystallography to determine how proteins interact.[4][3]
- 1994 – Pew Scholar [5]
- 1995 – Beckman Young Investigators Award[6]
- 1999 – MIT Innovators under 35[7]
- 2000 – AACR Award for Outstanding Achievement in Cancer Research
- 2003 – Paul Marks Prize for Cancer Research
- 2012 – Elected member of the National Academy of Sciences[3]
- 2014 – Elected fellow of the American Academy of Arts and Sciences[8]
- 2015 – Elected member of the Institute of Medicine[9]
- Cornelius P. Rhoads Memorial Award, American Association for Cancer Research
- DuPont-Merck Young Investigator Award, The Protein Society
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