Netrin G2

Netrin-G2 is a protein that in humans is encoded by the NTNG2 gene.^[5]

NTNG2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3TBD, 3ZYG, 3ZYI
Identifiers
Aliases	NTNG2, LHLL9381, Lmnt2, NTNG1, bA479K20.1, netrin G2, NEDBASH
External IDs	MGI: 2159341; HomoloGene: 13053; GeneCards: NTNG2; OMA:NTNG2 - orthologs
Gene location (Human) Chr. Chromosome 9 (human)[1] Band 9q34.13 Start 132,162,058 bp[1] End 132,244,526 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2 B|2 19.57 cM Start 29,084,553 bp[2] End 29,143,017 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in pancreatic ductal cell monocyte blood anterior cingulate cortex C1 segment right frontal lobe amygdala granulocyte Brodmann area 9 prefrontal cortex Top expressed in granulocyte neural layer of retina dentate gyrus of hippocampal formation granule cell primary visual cortex superior frontal gyrus lens muscle of thigh lip esophagus ventricular zone More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding molecular function Cellular component anchored component of membrane axon anchored component of plasma membrane membrane extracellular region cytosol plasma membrane intercellular bridge Flemming body Schaffer collateral - CA1 synapse glutamatergic synapse anchored component of presynaptic active zone membrane Biological process multicellular organism development cell differentiation axonogenesis nervous system development modulation of chemical synaptic transmission postsynaptic specialization assembly synaptic membrane adhesion regulation of presynapse assembly motor neuron axon guidance animal organ morphogenesis tissue development Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 84628 171171 Ensembl ENSG00000196358 ENSMUSG00000035513 UniProt Q96CW9 Q8R4F1 RefSeq (mRNA) NM_032536 NM_133500 NM_133501 NM_001305805 RefSeq (protein) NP_115925 NP_001292734 NP_598007 NP_598008 Location (UCSC) Chr 9: 132.16 – 132.24 Mb Chr 2: 29.08 – 29.14 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000196358 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000035513 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: NTNG2 netrin G2".

Further reading

• Nakajima D, Okazaki N, Yamakawa H, et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Res. 9 (3): 99–106. doi:10.1093/dnares/9.3.99. PMID 12168954.
• Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
• Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
• Nagase T, Nakayama M, Nakajima D, et al. (2001). "Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 8 (2): 85–95. doi:10.1093/dnares/8.2.85. PMID 11347906.
• Nakashiba T, Nishimura S, Ikeda T, Itohara S (2002). "Complementary expression and neurite outgrowth activity of netrin-G subfamily members". Mech. Dev. 111 (1–2): 47–60. doi:10.1016/S0925-4773(01)00600-1. PMID 11804778. S2CID 16856562.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Aoki-Suzuki M, Yamada K, Meerabux J, et al. (2005). "A family-based association study and gene expression analyses of netrin-G1 and -G2 genes in schizophrenia". Biol. Psychiatry. 57 (4): 382–93. doi:10.1016/j.biopsych.2004.11.022. PMID 15705354. S2CID 19932857.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.