Magnesium transporter protein 1

Magnesium transporter protein 1 is a protein that in humans is encoded by the MAGT1 gene.^[5][6]

MAGT1
Identifiers
Aliases	MAGT1, IAP, MRX95, OST3B, PRO0756, XMEN, bA217H1.1, RP11-217H1.1, magnesium transporter 1, SLC58A1, CDG1CC
External IDs	OMIM: 300715; MGI: 1914325; HomoloGene: 100678; GeneCards: MAGT1; OMA:MAGT1 - orthologs
Gene location (Human) Chr. X chromosome (human)[1] Band Xq21.1 Start 77,825,747 bp[1] End 77,899,271 bp[1]
Gene location (Mouse) Chr. X chromosome (mouse)[2] Band X|X D Start 105,011,690 bp[2] End 105,055,512 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in palpebral conjunctiva corpus epididymis tibia parotid gland germinal epithelium pericardium decidua visceral pleura parietal pleura seminal vesicula Top expressed in parotid gland lacrimal gland ciliary body seminal vesicula Paneth cell submandibular gland vestibular sensory epithelium islet of Langerhans migratory enteric neural crest cell iris More reference expression data BioGPS More reference expression data
Gene ontology Molecular function magnesium ion transmembrane transporter activity dolichyl-diphosphooligosaccharide-protein glycotransferase activity Cellular component integral component of membrane oligosaccharyltransferase complex plasma membrane integral component of plasma membrane membrane endoplasmic reticulum membrane azurophil granule membrane endoplasmic reticulum Biological process magnesium ion transport protein N-linked glycosylation cognition transmembrane transport magnesium ion transmembrane transport neutrophil degranulation protein glycosylation protein N-linked glycosylation via asparagine transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 84061 67075 Ensembl ENSG00000102158 ENSMUSG00000031232 UniProt Q9H0U3 Q9CQY5 RefSeq (mRNA) NM_032121 NM_001367916 NM_001190409 NM_025952 NM_001377002 NM_001377003 RefSeq (protein) NP_115497 NP_001354845 NP_001177338 NP_080228 NP_001363931 NP_001363932 Location (UCSC) Chr X: 77.83 – 77.9 Mb Chr X: 105.01 – 105.06 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

See also

• Magnesium transporter 1 family

References

1. GRCh38: Ensembl release 89: ENSG00000102158 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000031232 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Goytain A, Quamme GA (May 2005). "Identification and characterization of a novel mammalian Mg2+ transporter with channel-like properties". BMC Genomics. 6 (1): 48. doi:10.1186/1471-2164-6-48. PMC 1129089. PMID 15804357.
6. "MAGT1 magnesium transporter 1 [ Homo sapiens (human) ]".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Yu Y, Zhang C, Zhou G, et al. (2001). "Gene Expression Profiling in Human Fetal Liver and Identification of Tissue- and Developmental-Stage-Specific Genes through Compiled Expression Profiles and Efficient Cloning of Full-Length cDNAs". Genome Res. 11 (8): 1392–403. doi:10.1101/gr.175501. PMC 311073. PMID 11483580.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Kelleher DJ, Karaoglu D, Mandon EC, Gilmore R (2003). "Oligosaccharyltransferase isoforms that contain different catalytic STT3 subunits have distinct enzymatic properties". Mol. Cell. 12 (1): 101–11. doi:10.1016/S1097-2765(03)00243-0. PMID 12887896.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10". Nature. 429 (6990): 375–81. Bibcode:2004Natur.429..375D. doi:10.1038/nature02462. PMID 15164054.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Shibatani T, David LL, McCormack AL, et al. (2005). "Proteomic analysis of mammalian oligosaccharyltransferase reveals multiple subcomplexes that contain Sec61, TRAP, and two potential new subunits". Biochemistry. 44 (16): 5982–92. doi:10.1021/bi047328f. PMID 15835887.
• Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.