Lisinopril/hydrochlorothiazide
Combination drug used to treat high blood pressure From Wikipedia, the free encyclopedia
Lisinopril/hydrochlorothiazide, sold under the brand name Zestoretic among others, is a fixed-dose combination medication used for the treatment of high blood pressure (hypertension).[2] It contains lisinopril, an ACE inhibitor, and hydrochlorothiazide, a diuretic.[2][3] Typically, it becomes an option once a person is doing well on the individual components.[4] It is taken by mouth.[3]
Lisinopril (top) and hydrochlorothiazide (bottom) | |
| Combination of | |
|---|---|
| Lisinopril | ACE inhibitor |
| Hydrochlorothiazide | Thiazide diuretic |
| Clinical data | |
| Trade names | Zestoretic, Prinzide, others |
| Other names | lisinopril/hctz |
| AHFS/Drugs.com | Micromedex Detailed Consumer Information |
| MedlinePlus | a601070 |
| License data | |
| Pregnancy category |
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| Routes of administration | By mouth |
| ATC code | |
| Legal status | |
| Legal status | |
| Identifiers | |
| CAS Number | |
| KEGG | |
| (verify) | |
Common side effects include dizziness, headache, cough, and feeling tired.[2] Severe side effects may include angioedema and low blood pressure.[2] Use during pregnancy may harm the baby.[2]
The combination was approved for medical use in the United States in 1989.[3] It is on the World Health Organization's List of Essential Medicines.[5] It is available as a generic medication.[4] In 2022, the combination was the 53rd most commonly prescribed medication in the United States, with more than 12 million prescriptions.[6][7]
Medical uses
Lisinopril/hydrochlorothiazide is indicated for the treatment of hypertension, to lower blood pressure.[2]
Adverse effects
The US Food and Drug Administration prescription label for the combination contains a boxed warning about harm to the baby.[2]
References
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