Lafayette or La Fayette may refer to:
United States
- LaFayette, Alabama, a city
- Lafayette, California, a city
- Lafayette, Colorado, a home rule municipality
- LaFayette, Georgia, a city
- La Fayette, Illinois, a village
- Lafayette, Indiana metropolitan area
- Lafayette, Indiana, a city
- LaFayette, Kentucky, a town
- Lafayette, Louisiana metropolitan area
- Lafayette, Louisiana, a city
- Lafayette, Minnesota, a city
- LaFayette, New York, a town
- Lafayette, Ohio, a village
- Lafayette, Madison County, Ohio, a census-designated place
- Lafayette, Oregon, a city
- Lafayette, Tennessee, a city
- Lafayette, Virginia, a census-designated place
- Lafayette, Wisconsin (disambiguation)
- Faubourg Lafayette, Louisiana, a division in the city of New Orleans
- Mount Lafayette, New Hampshire
- Lafayette County (disambiguation)
- Lafayette Park (disambiguation)
- Lafayette Reservoir, Contra Costa County, California
- Lafayette River, entirely in the city of Norfolk, Virginia
- Lafayette Square (disambiguation)
- Lafayette Township (disambiguation)
- Lafayette Village, a historic district in North Kingstown, Rhode Island; on the National Register of Historic Places
- USS Lafayette, three US Navy ships
- Lafayette-class submarine, a class of US submarine
- French aircraft carrier La Fayette, a French aircraft carrier, formerly USS Langley (CVL-27)
- La Fayette-class frigate, a class of French frigates
- Fort Lafayette, a coastal fortification in the Narrows of New York Harbor
- Brigade La Fayette, also named Task Force La Fayette, a joint unit of the French forces in Afghanistan
- Lafayette Escadrille, a World War I squadron of the French Air Service composed largely of American pilots
- Lafayette Flying Corps, a name given to American volunteer pilots who flew for the French in World War I
- Lafayette Avenue (IND Fulton Street Line), Brooklyn, a New York City Subway station
- Broadway–Lafayette Street/Bleecker Street (New York City Subway) Manhattan
- Lafayette station (Indiana), an Amtrak station in Lafayette, Indiana
- Lafayette station (Louisiana), an Amtrak station in Lafayette, Louisiana
- Lafayette station (BART) is BART station in Lafayette, California
- Lafayette Square station, Buffalo, New York, Metro Rail station
- Lafayette Regional Airport Lafayette, Louisiana
- Lafayette Street a street in lower Manhattan, New York City
- Lafayette Boulevard a street in Detroit, Michigan
- Lafayette Bridge, spanning the Mississippi River in St Paul, Minnesota
- Rue La Fayette a street in Paris, France
- SS Lafayette, a shipwreck in Lake Superior, United States
- SS Mexique, a French ocean liner that was called Lafayette from 1915 until 1928