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Chemical compound From Wikipedia, the free encyclopedia
Dihydroquinidine (also called hydroquinidine) is an organic compound, a cinchona alkaloid closely related to quinine. The specific rotation is +226° in ethanol at 2 g/100 ml. A derivative of this molecule is used as chiral ligand in the AD-mix for Sharpless dihydroxylation.
This article needs additional citations for verification. (October 2008) |
Names | |
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IUPAC name
(S)-[(2R,4S,5R)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol | |
Other names
(9S)-10,11-Dihydro-6'-methoxycinchonan-9-ol | |
Identifiers | |
3D model (JSmol) |
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ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.007.578 |
PubChem CID |
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UNII | |
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Properties | |
C20H26N2O2 | |
Molar mass | 326.440 g·mol−1 |
Melting point | 169 to 172 °C (336 to 342 °F; 442 to 445 K) |
Pharmacology | |
C01BA13 (WHO) | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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The substance is also a class Ia antiarrhythmic medication.[1]
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