Hemogenic endothelium

Hemogenic endothelium or haemogenic endothelium^[1] is a special subset of endothelial cells scattered within blood vessels that can differentiate into haematopoietic cells.^[2]

The development of hematopoietic cells in the embryo proceeds sequentially from mesoderm through the hemangioblast to the hemogenic endothelium and hematopoietic progenitors.^[3] The relationship between the hemogenic endothelium and the hemangioblast is not clearly understood.^[1]

See also

• Hemangioblast

References

1. Yoshimoto, M; Yoder, MC (12 February 2009). "Developmental biology: Birth of the blood cell". Nature. 457 (7231): 801–3. Bibcode:2009Natur.457..801Y. doi:10.1038/457801a. PMC 2766277. PMID 19212393.
2. Swiers, G; Rode, C; Azzoni, E; de Bruijn, MF (December 2013). "A short history of hemogenic endothelium". Blood Cells, Molecules & Diseases. 51 (4): 206–12. doi:10.1016/j.bcmd.2013.09.005. PMC 4700588. PMID 24095001.
3. Lancrin, C; Sroczynska, P; Stephenson, C; Allen, T; Kouskoff, V; Lacaud, G (12 February 2009). "The haemangioblast generates haematopoietic cells through a haemogenic endothelium stage". Nature. 457 (7231): 892–5. Bibcode:2009Natur.457..892L. doi:10.1038/nature07679. PMC 2661201. PMID 19182774.