HEPPS (buffer)

HEPPS
	HEPPS
Names
	Preferred IUPAC name 3-[4-(2-Hydroxyethyl)piperazin-1-yl]propane-1-sulfonic acid
	Other names HEPPS, EPPS
Identifiers
CAS Number	16052-06-5;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:42298 ;
ChemSpider	76886 ;
ECHA InfoCard	100.036.528
PubChem CID	85255;
UNII	8JN5PQW99C ;
CompTox Dashboard (EPA)	DTXSID3066003 ;
	InChI InChI=1S/C9H20N2O4S/c12-8-7-11-5-3-10(4-6-11)2-1-9-16(13,14)15/h12H,1-9H2,(H,13,14,15) Key: OWXMKDGYPWMGEB-UHFFFAOYSA-N ; InChI=1/C9H20N2O4S/c12-8-7-11-5-3-10(4-6-11)2-1-9-16(13,14)15/h12H,1-9H2,(H,13,14,15) Key: OWXMKDGYPWMGEB-UHFFFAOYAP;
	SMILES O=S(=O)(O)CCCN1CCN(CCO)CC1;
Properties
Chemical formula	C9H20N2O4S
Molar mass	252.33 g·mol−1
Melting point	(decomposes)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

HEPPS (EPPS) is a buffering agent used in biology and biochemistry. The pKa of HEPPS is 8.00. It is ones of Good's buffers.^[1]

Quick Facts Names, Identifiers ...

Close

Research on mice with Alzheimer's disease-like amyloid beta plaques has shown that HEPPS can cause the plaques to break up, reversing some of the symptoms in the mice.^[2]^[3]^[4] HEPPS was reported to dissociate amyloid beta oligomers in patients' plasma samples enabling blood diagnosis of Alzheimer's disease.^[5]^[6]^[7]

[1]

[2]

[3]

[4]

[5]

[6]

[7]

HEPPS (buffer)

See also

References

Wikiwand - on