H2BFWT

H2B histone family, member W, testis-specific is a protein that in humans is encoded by the H2BFWT gene.^[3]

H2BW1
Identifiers
Aliases	H2BW1, H2B histone family member W, testis specific, H2BFWT, H2B.W histone 1, TH2B-175
External IDs	OMIM: 300507; HomoloGene: 128214; GeneCards: H2BW1; OMA:H2BW1 - orthologs
Gene location (Human) Chr. X chromosome (human)[1] Band Xq22.2 Start 104,011,147 bp[1] End 104,013,708 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle right testis placenta left testis right coronary artery prefrontal cortex tonsil superior frontal gyrus blood n/a More reference expression data BioGPS n/a
Gene ontology Molecular function DNA binding protein heterodimerization activity Cellular component nucleosome nuclear membrane membrane nucleus chromosome Biological process nucleosome assembly Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 158983 n/a Ensembl ENSG00000123569 n/a UniProt Q7Z2G1 n/a RefSeq (mRNA) NM_001002916 n/a RefSeq (protein) NP_001002916 n/a Location (UCSC) Chr X: 104.01 – 104.01 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the H2B histone family that is specifically expressed in sperm nuclei. A polymorphism in the 5' UTR of this gene is associated with male infertility.[provided by RefSeq, Jan 2010].^[3]