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Chemical compound From Wikipedia, the free encyclopedia
β-Guanidinopropionic acid, also referred to as guanidinopropionic acid, beta-guanidinopropionic acid or β-GPA, is a dietary supplement.
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Names | |
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IUPAC name
3-Carbamimidamidopropanoic acid[1] | |
Other names | |
Identifiers | |
3D model (JSmol) |
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3DMet | |
1705262 | |
ChEBI | |
ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.005.937 |
EC Number |
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KEGG | |
MeSH | guanidopropionic+acid |
PubChem CID |
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RTECS number |
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UNII | |
CompTox Dashboard (EPA) |
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Properties | |
C4H9N3O2 | |
Molar mass | 131.135 g·mol−1 |
Appearance | White crystals |
Odor | Odourless |
log P | −1.472 |
Acidity (pKa) | 4.219 |
Basicity (pKb) | 9.778 |
Hazards | |
GHS labelling: | |
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Warning | |
H315, H319, H335 | |
P261, P305+P351+P338 | |
Related compounds | |
Related alkanoic acids |
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Related compounds |
Dimethylacetamide |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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β-Guanidinopropionic acid is a white crystalline powder soluble in water (50 mg/ml-clear, colorless solution).[2]
Studies on animals (rats, monkeys, hamsters) show that acidic guanidine derivatives such as β-GPA can ameliorate hyperglycemia in animal models of noninsulin-dependent diabetes.[3]
Though the oral availability of β-GPA is well established, the basic uptake mechanism has not been studied yet.[4]
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