Grand Canyon most often refers to:
Grand Canyon may also refer to:
- Grand Canyon of the Colorado River, a 1892-1908 painting by Thomas Moran
- The Grand Canyon of the Yellowstone (1872), a 1872 painting by Thomas Moran
- The Grand Canyon of the Yellowstone (1893-1901 painting), a 1893-1901 painting by Thomas Moran
- Grand Canyon (1949 film), an American Western
- Grand Canyon (1958 film), a Disney documentary film
- Grand Canyon (1991 film), an American drama film
- Grand Canyon: The Hidden Secrets, a 1984 IMAX documentary
- Grand Canyon (book), a 2017 children's picture book by Jason Chin
- Grand Canyon: A Different View, 2003 book edited by Tom Vail
- Grand Canyon Suite, a 1931 suite for orchestra by Ferde Grofé
- "Grand Canyon", a song by Puscifer from the 2015 album Money Shot
- "Grand Canyon", a song by The Magnetic Fields from their 1999 album 69 Love Songs
- Grand Canyon West, Arizona, a CDP
- Grand Canyon (Greenland)
- Grand Canyon (Missouri), U.S.
- Grand Canyon of the Elwha, Washington, U.S.
- Grand Canyon of the Fraser, British Columbia, Canada
- Grand Canyon of the Nechako, British Columbia, Canada
- Grand Canyon of the Pacific, Hawaiian Islands of the U.S.
- Grand Canyon of Pennsylvania, or Pine Creek Gorge, Pennsylvania, U.S.
- Grand Canyon of the Stikine, British Columbia, Canada
- Grand Canyon of the Tuolumne, California, U.S.
- Grand Canyon of the Yellowstone, Wyoming, U.S.
- Valles Marineris, on Mars, is also known as the Grand Canyon