Germ or germs may refer to:
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germ in Wiktionary, the free dictionary.
- Germ (microorganism), an informal word for a pathogen
- Germ cell, cell that gives rise to the gametes of an organism that reproduces sexually
- Germ layer, a primary layer of cells that forms during embryonic development
- Cereal germ, the reproductive part of a cereal grain
- Tooth germ, an aggregation of cells that eventually forms a tooth
- Germ theory of disease, which states that some diseases are caused by microorganisms
- Germ (mathematics), an object in a topological space that captures local properties
- Germ, Hautes-Pyrénées, a commune in the Hautes-Pyrénées department of southwestern France
- Germ Hofma (born 1925), Dutch football player in the 1940s and 1950s
- Germination, the process by which an organism grows from a seed or similar structure
- Stem cell, biological cells that can differentiate into other types of cells