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Chemical compound From Wikipedia, the free encyclopedia
Cefapirin (INN, also spelled cephapirin) is an injectable, first-generation cephalosporin antibiotic. It is marketed under the trade name Cefadyl. Production for use in humans has been discontinued in the United States.[1]
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AHFS/Drugs.com | International Drug Names |
MedlinePlus | a601206 |
Routes of administration | Intravenous, intramuscular |
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ECHA InfoCard | 100.040.409 |
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Formula | C17H17N3O6S2 |
Molar mass | 423.46 g·mol−1 |
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It also has a role in veterinary medicine as Metricure, an intrauterine preparation, and combined with prednisolone in Mastiplan, an intramammary preparation. Both are licensed in cattle.[citation needed]
In one of the syntheses, 7-aminocephalosporanic acid (7-ACA) is reacted with bromoacetyl chloride to give the amide. The halo group is then displaced by 4-thiopyridine.[2]
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