C is the third letter in the Latin alphabet.
C or c may also refer to:
- Troponin C, one of the three troponins
- Carbon, symbol C, a chemical element
- Atomic carbon or C
- ATC code C or cardiovascular system, a section of the Anatomical Therapeutic Chemical Classification System
- Haplogroup C (mtDNA), a human mitochondrial DNA (mtDNA) haplogroup
- Haplogroup C-M130 (Y-DNA), a Y-chromosomal DNA (Y-DNA) haplogroup once called simply C
- Cytosine, nucleic acid
- C (or Cys), an abbreviation for the amino acid cysteine
- C, a prefix for astronomical objects listed in the Caldwell catalogue, ranging from C1 to C109
- C, a prefix for astronomical star clusters, which follow the IAU's "Chhmm±ddd" format
- c, the speed of light in vacuum
- c, the speed of sound
- c, the specific heat capacity of a substance
- c, any constant
- C, capacitance
- C, symbol of coulomb
- Charm quark (
c
)
- C-value, DNA contained within a haploid nucleus
- C, a digit meaning twelve in hexadecimal and other positional numeral systems with a radix of 13 or greater
- C, the constant of integration
- C, in Roman numerals, the symbol for 100
- C, , or , the set of all complex numbers
- ℭ or , the cardinality of the continuum
- C, the set of continuous functions
- The combination or "choose" function
- c space, the space of all convergent sequences in functional analysis
- Prefix "c", to specify a column number as in-source-locator in old citations
- С, a letter of the Cyrillic alphabet
- C (anime), by Tatsunoko Production, Fuji TV
- C (grade), a satisfactory grade in education
- C (plastic toy), a plastic toy from former Czechoslovakia
- Citigroup, Inc.'s stock ticker symbol
- Gaius or C
- Center Party (Sweden), a Swedish political party
- Mansfield Smith-Cumming or C (1859–1923), Chief of the SIS, the UK Secret Intelligence Service, also known as MI6
- His successors as Chief of the SIS have since been generally known by his alias, C
- C, also known as Max Denbigh, a character played by Andrew Scott in the film Spectre
- c (IPA) in the International Phonetic Alphabet (IPA), the voiceless palatal stop
- Dominical letter C for a common year starting on Friday
- C, the production code for the 1964 Doctor Who serial The Edge of Destruction
- Charlie, the military time zone code for UTC+03:00
- c, alternative name for Grimes
- Farmall C, a tractor produced by International Harvester from 1948 to 1951
- C (restaurant), a restaurant in Tampere, Finland
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