CSF/serum albumin ratio

CSF/serum albumin ratio is a test performed to compare the levels of albumin in the cerebrospinal fluid and the serum.

CSF/serum albumin ratio
LOINC	1756-6

It is useful as a measure of the integrity of the blood–brain barrier.^[1][2][3]

References

Pathophysiology sample values

BMP/ELECTROLYTES:
Na+ = 140	Cl− = 100	BUN = 20	/ Glu = 150 \
K+ = 4	CO2 = 22	PCr = 1.0
ARTERIAL BLOOD GAS:
HCO3− = 24	paCO2 = 40	paO2 = 95	pH = 7.40
ALVEOLAR GAS:
	pACO2 = 36	pAO2 = 105	A-a g = 10
OTHER:
Ca = 9.5	Mg2+ = 2.0	PO4 = 1
CK = 55	BE = −0.36	AG = 16
SERUM OSMOLARITY/RENAL:
PMO = 300	PCO = 295	POG = 5	BUN:Cr = 20
URINALYSIS:
UNa+ = 80	UCl− = 100	UAG = 5	FENa = 0.95
UK+ = 25	USG = 1.01	UCr = 60	UO = 800
PROTEIN/GI/LIVER FUNCTION TESTS:
LDH = 100	TP = 7.6	AST = 25	TBIL = 0.7
ALP = 71	Alb = 4.0	ALT = 40	BC = 0.5
		AST/ALT = 0.6	BU = 0.2
AF alb = 3.0	SAAG = 1.0		SOG = 60
CSF:
CSF alb = 30	CSF glu = 60	CSF/S alb = 7.5	CSF/S glu = 0.6

1. Luque FA, Jaffe SL (2007). "Cerebrospinal fluid analysis in multiple sclerosis". Int. Rev. Neurobiol. International Review of Neurobiology. 79: 341–56. doi:10.1016/S0074-7742(07)79015-3. ISBN 978-0-12-373736-6. PMID 17531849.
2. Anckarsäter H, Forsman A, Blennow K (July 2005). "Increased CSF/serum albumin ratio: a recurrent finding in violent offenders". Acta Neurol. Scand. 112 (1): 48–50. doi:10.1111/j.1600-0404.2005.00433.x. PMID 15932356. S2CID 32792323.
3. Algotsson A, Winblad B (June 2007). "The integrity of the blood–brain barrier in Alzheimer's disease". Acta Neurol. Scand. 115 (6): 403–8. doi:10.1111/j.1600-0404.2007.00823.x. PMID 17511849. S2CID 21025192.