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Chemical compound From Wikipedia, the free encyclopedia
Cytidine diphosphate glucose, often abbreviated CDP-glucose, is a nucleotide-linked sugar consisting of cytidine diphosphate and glucose.[1][2] This nucleotide saccharide participates in the synthesis of deoxy sugars such as paratose and tyvelose.[3]
Names | |
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IUPAC name
Cytidine 5′-(α-D-glucopyranosyl trihydrogen diphosphate) | |
Systematic IUPAC name
O1-{[(2R,3S,4R,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxyoxolan-2-yl]methyl} O3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] dihydrogen diphosphate | |
Other names
CDP-glucose | |
Identifiers | |
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CompTox Dashboard (EPA) |
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Properties | |
C15H25N3O16P2 | |
Molar mass | 565.318 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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CDP-glucose is produced from CTP and glucose-1-phosphate by the enzyme glucose-1-phosphate cytidylyltransferase.[3]
CDP-glucose is an important metabolite in certain bacteria, which synthesize O antigens from it.[3] CDP-glucose can also be used as a substrate for glycogenin, along its native substrate, UDP-glucose. The same is true for TDP-glucose.[4]
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