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From Wikipedia, the free encyclopedia
Blood–brain barrier disruption is the surgical process whereby drugs are used to create openings between cells in the blood–brain barrier.[1]
The blood–brain barrier (BBB) is protected by a network of blood vessels and tissue that shields it from harmful substances. This protection also stops anti-cancer drugs from getting to the brain. To treat brain tumours and other brain related diseases,[2][3] blood–brain barrier disruption is needed for the anti-cancer drugs to be infused into an artery that goes to the brain.[1]
Studies have shown that blood–brain barrier disruption can cause diseases in the central nervous system.[4][5]