Adapalene/benzoyl peroxide, sold under the brand name Epiduo among others, is a fixed-dose combination medication for the treatment of severe acne vulgaris.[1][2] It consists of a combination of adapalene and benzoyl peroxide in a topical gel formulation.[1][2]
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| Combination of | |
|---|---|
| Adapalene | Retinoid |
| Benzoyl peroxide | Peroxide |
| Clinical data | |
| Trade names | Epiduo, Epiduo Forte |
| Routes of administration | Topical |
| ATC code | |
| Legal status | |
| Legal status | |
| Identifiers | |
| CAS Number | |
| KEGG | |
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It is available as a generic medication.[3]
Medical uses
Adapalene/benzoyl peroxide is indicated for the topical treatment of acne vulgaris.[1][2]
Side effects
Research
Meta-analysis of clinical trials has shown this combined therapy to be more effective than either of its ingredients by themselves.[4]
The use of adapalene/benzoyl peroxide in combination with oral antibiotics (lymecycline) has been studied;[5] the combination was well tolerated and showed an improved success rate compared to those receiving only antibiotics (47.6% vs. 33.7%, P = 0.002).
References
External links
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