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Medical condition From Wikipedia, the free encyclopedia
Arachnoid cysts are cerebrospinal fluid covered by arachnoidal cells and collagen[1] that may develop between the surface of the brain and the cranial base or on the arachnoid membrane, one of the three meningeal layers that cover the brain and the spinal cord.[2] Primary arachnoid cysts are a congenital disorder whereas secondary arachnoid cysts are the result of head injury or trauma.[3] Most cases of primary cysts begin during infancy; however, onset may be delayed until adolescence.[2]
| Arachnoid cyst | |
|---|---|
.jpg) | |
| An MRI of a 25-year-old woman with left frontotemporal arachnoid cyst. | |
| Specialty | Neurosurgery  |
Patients with arachnoid cysts may never show symptoms, even in some cases where the cyst is large. Therefore, while the presence of symptoms may provoke further clinical investigation, symptoms independent of further data cannot—and should not—be interpreted as evidence of a cyst's existence, size, location, or potential functional impact on the patient.[citation needed]
Symptoms vary by the size and location of the cyst(s), though small cysts usually have no symptoms and are discovered only incidentally.[2] On the other hand, a number of symptoms may result from large cysts:
The exact cause of arachnoid cysts is not known. Researchers believe that most cases of arachnoid cysts are developmental malformations that arise from the unexplained splitting or tearing of the arachnoid membrane.[citation needed]
In some cases, arachnoid cysts occurring in the middle fossa are accompanied by underdevelopment (hypoplasia) or compression of the temporal lobe. The exact role that temporal lobe abnormalities play in the development of middle fossa arachnoid cysts is unknown.[citation needed]
There are some cases where hereditary disorders have been connected with arachnoid cysts.[18]
Some complications of arachnoid cysts can occur when a cyst is damaged because of minor head trauma.[19] Trauma can cause the fluid within a cyst to leak into other areas (e.g., subarachnoid space). Blood vessels on the surface of a cyst may tear and bleed into the cyst (intracystic hemorrhage), increasing its size. If a blood vessel bleeds on the outside of a cyst, a collection of blood (hematoma) may result. In the cases of intracystic hemorrhage and hematoma, the individual may have symptoms of increased pressure within the cranium and signs of compression of nearby nerve (neural) tissue.[citation needed]
Some scientists debate whether arachnoid cysts are a true congenite condition or if this should be separated from secondary cysts.[20] A recent study shows differences in communication between the arachnoid cyst and the subarachnoid space by CT cisternography.[21] A comparison of arachnoid cyst fluid and CSF in a series of patients show differences in chemical composition.[22]
Arachnoid cysts can also occur secondary to other disorders such as Marfan syndrome, arachnoiditis, or agenesis of the corpus callosum.[citation needed]
Diagnosis is principally by MRI. Frequently, arachnoid cysts are incidental findings on MRI scans performed for other clinical reasons. In practice, diagnosis of symptomatic arachnoid cysts requires symptoms to be present, and many with the disorder never develop symptoms.[citation needed]
Additional clinical assessment tools that can be useful in evaluating a patient with arachnoid cysts include the mini-mental state examination (MMSE), a brief questionnaire-based test used to assess cognition.[9]
Arachnoid cysts can be found on the brain or on the spine. Intracranial arachnoid cysts usually occur adjacent to the arachnoidal cistern.[23] Spinal arachnoid cysts may be extradural, intradural, or perineural and tend to present with signs and symptoms indicative of a radiculopathy.[23]
Arachnoid cysts may also be classified as primary (congenital) or secondary (acquired) and have been reported in humans, cats, and dogs.[24]
Arachnoid cysts can be relatively asymptomatic or present with insidious symptoms; for this reason, diagnosis is often delayed.[citation needed]
Most arachnoid cysts are asymptomatic and do not require treatment. Treatment may be necessary when symptomatic.[2] A variety of procedures may be used to decompress (remove pressure from) the cyst.
Most arachnoid cysts are asymptomatic, and do not require treatment. Where complications are present, leaving arachnoid cysts untreated may cause permanent severe neurological damage due to the progressive expansion of the cyst(s) or hemorrhage (bleeding).[2] However, with treatment most individuals with symptomatic arachnoid cysts do well.[citation needed]
More specific prognoses are listed below:
Arachnoid cysts are seen in up to 1.1% of the population[34][35] with a gender distribution of 2:1 male:female.[36] Only 20% of these have symptoms, usually from secondary hydrocephalus.[34]
A study that looked at 2,536 healthy young males found a prevalence of 1.7% (95% CI 1.2 to 2.3%). Only a small percentage of the detected abnormalities require urgent medical attention.[37]
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