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Chemical compound From Wikipedia, the free encyclopedia
Motexafin lutetium is a texaphyrin, marketed as Antrin by Pharmacyclics Inc.
Names | |
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Other names
Antrin; Lu texaphyrin; Lu-Tex; Lutetium texaphyrin; Lutrin; Optrin; PCI 0123 | |
Identifiers | |
3D model (JSmol) |
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PubChem CID |
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UNII | |
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Properties | |
C52H72LuN5O14 | |
Molar mass | 1166.136 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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It is a photosensitiser for use in photodynamic therapy to treat skin conditions and superficial cancers.
It has also been tested for use in photoangioplasty (photodynamic treatment of diseased arteries).[1]
It is photoactivated by 732 nm light which allows greater depth of penetration.[2]
Phase II clinical trials were in progress in 1999.[3]
A phase I trial for prostate cancer reported in 2009.[4]
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