Androvax

Androvax, also known as androstenedione:human serum albumin conjugate, is an immunogen and vaccine against androstenedione that is used in veterinary medicine to increase the ovulation rate and number of lambs born to ewes.^[1][2][3] It is a conjugate of androstenedione and human serum albumin.^[1][3] The drug is marketed in New Zealand.^[1][3]

Androvax

Combination of
Androstendione	Androstane steroid
Human serum albumin	Serum protein
Clinical data
Trade names	Androvax
Other names	Androstenedione:human serum albumin conjugate
AHFS/Drugs.com	Monograph
Legal status
Legal status	US: ℞-only
Identifiers
CAS Number	128280-53-5
ChemSpider	None

Androvax produces immunity against androstenedione, and the generation of antibodies against androstenedione decreases circulating levels of androstenedione.^[1] In addition, since androstenedione is the major precursor of estrogens, estrogen levels are decreased as well.^[1] This is thought to result in reduced negative feedback on the hypothalamic-pituitary-gonadal axis and increased gonadotropin secretion, which in turn improves fertility and fecundity.^[1]

See also

• Ovandrotone albumin

References

1. Jindal SK, Sharma MC (2010). Biotechnology in Animal Health and Production. New India Publishing. pp. 77–. ISBN 978-93-80235-35-6.
2. Reproductive Technologies in Farm Animals. CABI. 2004. pp. 206–. ISBN 978-0-85199-049-1.
3. "Androvax Label" (PDF). Schering-Plough Animal Health Ltd. MSD Animal Health.