9-Hydroxyhexahydrocannabinol

9-Hydroxyhexahydrocannabinol (9-OH-HHC) is a semi-synthetic derivative of tetrahydrocannabinol. It is formed as an impurity in the synthesis of Delta-8-THC,^[1] and retains activity in animal studies though with only around 1/10 the potency of Δ⁹-THC, with the 9α- and 9β- enantiomers having around the same potency.^[2]

9-Hydroxyhexahydrocannabinol

Identifiers
IUPAC name (6aR,10aR)-6,6,9-trimethyl-3-pentyl-7,8,10,10a-tetrahydro-6aH-benzo[c]chromene-1,9-diol
CAS Number	36028-45-2 52522-56-2
PubChem CID	71579182
ChemSpider	148443
Chemical and physical data
Formula	C21H32O3
Molar mass	332.484 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCCCCC1=CC(=C2C3CC(CCC3C(OC2=C1)(C)C)(C)O)O
InChI InChI=1S/C21H32O3/c1-5-6-7-8-14-11-17(22)19-15-13-21(4,23)10-9-16(15)20(2,3)24-18(19)12-14/h11-12,15-16,22-23H,5-10,13H2,1-4H3/t15-,16-,21?/m1/s1 Key:KSGRDIFQZVURIF-BLRYKZMTSA-N

See also

• 8-Hydroxyhexahydrocannabinol
• 9-Nor-9β-hydroxyhexahydrocannabinol
• 11-Hydroxyhexahydrocannabinol
• 11-Hydroxy-THC
• 11-Hydroxy-Delta-8-THC
• Cannabicitran
• Cannabitriol
• Delta-10-THC
• Hexahydrocannabinol