3-Hydroxypicolinic acid

3-Hydroxy picolinic acid is a picolinic acid derivative and is a member of the pyridine family. It is used as a matrix for nucleotides in MALDI mass spectrometry analyses^[1] and the synthesis of favipiravir.

3-Hydroxypicolinic acid

Names
Preferred IUPAC name 3-Hydroxypyridine-2-carboxylic acid
Other names 3-Hydroxypicolinic acid 3-Hydroxy-2-pyridinecarboxylic acid
Identifiers
CAS Number	874-24-8 Y
3D model (JSmol)	Interactive image Interactive image
ChEBI	CHEBI:63432 N
ChemSpider	12827 Y
ECHA InfoCard	100.011.690
PubChem CID	13401
UNII	XV7XP64JR5 Y
CompTox Dashboard (EPA)	DTXSID80236320
InChI InChI=1S/C6H5NO3/c8-4-2-1-3-7-5(4)6(9)10/h1-3,8H,(H,9,10) Y Key: BRARRAHGNDUELT-UHFFFAOYSA-N Y InChI=1/C6H5NO3/c8-4-2-1-3-7-5(4)6(9)10/h1-3,8H,(H,9,10) Key: BRARRAHGNDUELT-UHFFFAOYAC
SMILES C1=CC(=C(N=C1)C(=O)O)O c1cc(c(nc1)C(=O)O)O
Properties
Chemical formula	C6H5NO3
Molar mass	139.109
Appearance	Light yellow needles
Melting point	208 to 212 °C (406 to 414 °F; 481 to 485 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references

See also

• Matrix-assisted laser desorption/ionization
• Sinapinic acid
• Picolinic acid
• α-Cyano-4-hydroxycinnamic acid

References

1. Wu KJ, Steding A, Becker CH (1993). "Matrix-assisted laser desorption time-of-flight mass spectrometry of oligonucleotides using 3-hydroxypicolinic acid as an ultraviolet-sensitive matrix". Rapid Commun. Mass Spectrom. 7 (2): 142–6. Bibcode:1993RCMS....7..142W. doi:10.1002/rcm.1290070206. PMID 8457722.