3,4-Methylenedioxyphentermine

3,4-Methylenedioxyphentermine (MDPH) is a lesser-known drug of the amphetamine family. MDPH was first synthesized by Alexander Shulgin. Very little data exists about the pharmacological properties, metabolism, and toxicity of MDPH.

MDPH

Names
Preferred IUPAC name 1-(2H-1,3-Benzodioxol-5-yl)-2-methylpropan-2-amine
Other names MDP; MDPH; 3,4-Methylenedioxyphentermine; 3,4-Methylenedioxy-alpha,alpha-dimethyl-1-ethane
Identifiers
CAS Number	39235-63-7 Y
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL126226
ChemSpider	15204207 Y
PubChem CID	13020598
UNII	WF9K2PM8J8
CompTox Dashboard (EPA)	DTXSID90515395
InChI InChI=1S/C11H15NO2/c1-11(2,12)6-8-3-4-9-10(5-8)14-7-13-9/h3-5H,6-7,12H2,1-2H3 N Key: OIZBHKBNZXRXSM-UHFFFAOYSA-N N InChI=1/C11H15NO2/c1-11(2,12)6-8-3-4-9-10(5-8)14-7-13-9/h3-5H,6-7,12H2,1-2H3 Key: OIZBHKBNZXRXSM-UHFFFAOYAY
SMILES NC(C)(C)CC1=CC(OCO2)=C2C=C1
Properties
Chemical formula	C11H15NO2
Molar mass	193.246 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references

In his book PiHKAL (Phenethylamines i Have Known And Loved), the dosage range is listed as 160–240 mg, and the duration as 3–5 hours.^[1] MDPH's effects are very similar to those of MDA: they both are smooth and "stoning," and do not cause any visuals. They also alter dreams and dream patterns. Shulgin describes MDPH as a promoter; it promotes the effects of other drugs, similarly to 2C-D.

The N-methyl derivative, 3,4-methylenedioxy-N-methylphentermine (MDMPH), has been described by Shulgin as lacking MDMA-like effects.^[2] Accordingly, MDMPH, as well as MDPH, were found to be inactive as serotonin releasing agents in vitro.^[2][3]

Legality

United Kingdom

This substance is a Class A drug in the Drugs controlled by the UK Misuse of Drugs Act.^[4]

See also

• 3,4-Dichloroamphetamine
• Cericlamine
• Chlorphentermine
• Cloforex
• Clortermine
• Etolorex
• Methylenedioxyphenmetrazine
• Phentermine