User:Jea3c/sandbox
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COMT inhibitors are a class of drugs that inhibit the action of the enzyme catechol-O-methyl transferase (COMT). COMT is a Phase II biotransformation enzyme that metabolizes molecules that contain a catechol group, including the catecholamine group of neurotransmitters (dopamine, epinephrine, and norepinephrine)[1]. COMT inhibitors are used in the treatment of Parkinson's disease in combination with levodopa (L-DOPA) and a DOPA decarboxylase inhibitor (DDCI). The addition of a COMT inhibitor to the DDCI treatment can help to further stabilize levels of levodopa in the periphery and increase the amount that reaches the brain, where it can be converted to dopamine[2].
This is a user sandbox of Jea3c. You can use it for testing or practicing edits. This is not the sandbox where you should draft your assigned article for a dashboard.wikiedu.org course. To find the right sandbox for your assignment, visit your Dashboard course page and follow the Sandbox Draft link for your assigned article in the My Articles section. |