User:Amylaid/Alzheimer's disease in African Americans
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Alzheimer's disease in African Americans is becoming a rising topic of interest in Alzheimer's care, support, and scientific research, as African Americans are disproportionately affected by Alzheimer's. Recent research on Alzheimer's has shown that there are clear disparities in the disease among racial groups,[1] with higher prevalence and incidence in African Americans than the overall average. Pathologies for Alzheimer’s also seem to manifest differently in African Americans, including with neuroinflammation markers, cognitive decline, and biomarkers. Genetics are a huge risk factor for Alzheimer’s, but known high-risk genes for the disease have different effect sizes in African Americans compared to other racial groups. Higher rates of comorbidity could also explain the higher prevalence of Alzheimer's in African Americans.
There are also socioeconomic disparities—such as education, representation in clinical trials, and cost of care services—between African Americans and other racial groups that are important for the care and research of Alzheimer's in African Americans.