User:Coldbringer/sandbox
Medical condition / From Wikipedia, the free encyclopedia
Gandy–Gamna nodules, Gandy–Gamna bodies or siderotic nodules are small yellow-brown, brown or rust-coloured foci found in the spleen in patients with splenomegaly due to portal hypertension and sickle cell disease. They consist of fibrous tissue with haemosiderin and calcium deposits, and probably form due to scarring at sites of small perivascular haemorrhages.[1] They are visible on MRI scanning due to the presence of haemosiderin.
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Other names include hemosiderotic nodules[2], Gandy-Gamna-De Gaetani areas[3], sclerosiderotic areas of Gandy-Gamna[4], Gandy-Gamna lesions[5], sclerotic calciosiderosis[5], sclerosiderotic granulomatosis.[6] and because of their rusty colour on gross inspection, tobacco flecks.[7]