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Class of enzymes From Wikipedia, the free encyclopedia
In enzymology, an ubiquitin-calmodulin ligase (EC 6.3.2.21) is an enzyme that catalyzes the chemical reaction
ubiquitin-calmodulin ligase | |||||||||
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Identifiers | |||||||||
EC no. | 6.3.2.21 | ||||||||
CAS no. | 119632-60-9 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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The 3 substrates of this enzyme are ATP, calmodulin, and ubiquitin, whereas its 3 products are AMP, diphosphate, and (ubiquitin)n-calmodulin.
This enzyme belongs to the family of ligases, specifically those forming carbon-nitrogen bonds as acid-D-amino-acid ligases (peptide synthases). The systematic name of this enzyme class is calmodulin:ubiquitin ligase (AMP-forming). Other names in common use include ubiquityl-calmodulin synthase, ubiquitin-calmodulin synthetase, ubiquityl-calmodulin synthetase, and uCaM-synthetase.
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