Tyrosine—arginine ligase
Class of enzymes / From Wikipedia, the free encyclopedia
In enzymology, a tyrosine—arginine ligase (EC 6.3.2.24) is an enzyme that catalyzes the chemical reaction
- ATP + L-tyrosine + L-arginine
AMP + diphosphate + L-tyrosyl-L-arginine
Quick Facts Identifiers, EC no. ...
Tyrosine—arginine ligase | |||||||||
---|---|---|---|---|---|---|---|---|---|
Identifiers | |||||||||
EC no. | 6.3.2.24 | ||||||||
CAS no. | 116036-78-3 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
|
Close
The 3 substrates of this enzyme are ATP, L-tyrosine, and L-arginine, whereas its 3 products are AMP, diphosphate, and L-tyrosyl-L-arginine.
This enzyme belongs to the family of ligases, specifically those forming carbon-nitrogen bonds as acid-D-amino-acid ligases (peptide synthases). The systematic name of this enzyme class is L-tyrosine:L-arginine ligase (AMP-forming). Other names in common use include tyrosyl-arginine synthase, kyotorphin synthase, kyotorphin-synthesizing enzyme, and kyotorphin synthetase.