Twisted Sister may refer to:
- Twisted Sisters, a 2016 U.S. thriller also known as Sorority Nightmare starring Sierra McCormick and Cassidy Gifford
- Twisted Sisters (comic), an underground comix series by Aline Kominsky-Crumb and Diane Noomin
- "Twisted Sisters", a term used to refer to a proposed development in the Texpark site in Halifax, Nova Scotia, Canada
See also
- Twisted Sister, a heavy-metal band
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