Sophie is a feminine given name, another version of Sophia, from the Greek word for "wisdom".
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Born in 1600s and 1700s
- Sophie of Anhalt-Zerbst (1729–1796), later Empress Catherine II of Russia
- Sophie Amalie of Brunswick-Lüneburg (1628–1685), Queen consort of Denmark-Norway
- Sophie Blanchard (1778–1819), French balloonist
- Sophie Dorothea of Württemberg (1759–1828), second wife of Tsar Paul I of Russia
- Sophie Dawes, Baronne de Feuchères (c. 1795–1840), English baroness
- Sophie Germain (1776–1831), French mathematician
- Sophie Piper (1757–1816), Swedish countess
- Sophie Schröder (1781–1868), German actress
- Sophie von La Roche (1730–1807), German author
- Princess Sophie of Erbach-Erbach, (1725–1795), Princess consort of Nassau-Saarbrücken
Born 1790–1918
- Sophie, Duchess of Alencon (1847–1897), wife of Prince Ferdinand, Duke of Alençon
- Sophie, Archduchess of Austria (1855–1857), first child of Franz Joseph I, Emperor of Austria, and Elisabeth of Bavaria
- Sophie of Bavaria (1805–1872), mother of Emperor Franz Joseph I of Austria
- Sophie, Countess of Ségur (1799–1874), Russian-French writer
- Sophie of Sweden (1801–1865), Grand Duchess of Baden
- Sophie von Hatzfeldt (1805–1881), German Worker's Rights Advocate, "The Red Countess"
- Sophie Adelheid, Duchess in Bavaria (1875–1957), German nobility
- Sophie Adlersparre (1823–1895), Swedish women's rights activist
- Sophie Atkinson (1876–1972), English painter
- Sophie Bledsoe Aberle (1896–1996), American anthropologist
- Sophie Braslau (1892–1935), American contralto
- Sophie Chotek (1868–1914), wife of Archduke Franz Ferdinand, also assassinated
- Sophie Daguin (1801–1881), French ballerina
- Sophie Gengembre Anderson (1823–1903), French-British artist
- Sophie Kerr (1880–1965), American author
- Sophie Ley (1849–1918), German painter
- Sophie Masloff (1917–2014), mayor of Pittsburgh
- Sophie Mannerheim (1863–1928), Finnish nurse
- Sophie Dora Spicer Maude (1854–?), English writer
- Sophie Pemberton (1869–1950), Canadian painter
- Sophie Rostopchine (1799–1874), French writer
- Sophie Schulz (1905–1975), Austrian politician
- Sophie Sooäär (1914–1996), Estonian actress
- Sophie Tucker (1887–1966), American entertainer
- Sophie Treadwell (1885–1970), American writer
Born after 1918
- Sophie, Hereditary Princess of Liechtenstein (born 1967), German member of the House of Wittelsbach by birth
- Sophie Bradley (born 1994), English footballer
- Sophie, Princess of Prussia (born 1978), wife of Georg Friedrich, Prince of Prussia, head of the House of Hohenzollern
- Sophie, Princess of Windisch-Graetz (born 1959), Austrian member of the House of Habsburg-Lorraine by birth and the Austrian House of Windisch-Graetz by marriage
- Sophie, Duchess of Edinburgh (born 1965), British wife of Prince Edward, Duke of Edinburgh
- Sophie Abelson (born 1986), English actress
- Sophie Adriansen (born 1982), French writer
- Sophie Aguie (born 1996), Ivorian footballer
- Sophie Ainsworth (born 1989), British sailor
- Sophie Albert (born 1990), Filipino actress
- Sophie Aldred (born 1962), British actress
- Sophie Anderson (1987–2023), English adult actress & internet personality
- Sophie Anderton (born 1977), English model
- Sophie Aston (born 1970), British painter
- Sophie Auconie (born 1963), French politician
- Sophie Auster (born 1987), American singer-songwriter and actress
- Sophie Austin (born 1984), English actress
- Sophie Baggaley (born 1996), English footballer
- Sophie Barjac (born 1957), French actress
- Sophie Barker (born 1971), English singer
- Sophie Barker (footballer) (born 1990), English footballer
- Sophie Barthes (born 1974), French-American film director
- Sophie Beem (born 1999), American singer
- Sophie Bellon (born 1961), French businesswoman
- Sophie Bennett (born 1989), Canadian singer
- Sophie Berge (born 1964), French yacht racer
- Sophie Bevan (born 1983), British soprano
- Sophie Bissonnette (born 1964), French-Canadian director
- Sophie Black (born 1958), American prize-winning poet
- Sophie Blackall, Australian artist
- Sophie de Boer (born 1990), Dutch racing cyclist
- Sophie Body-Gendrot (1942–2018), French political scientist, criminologist and sociologist
- Sophie Boilley (born 1989), French biathlete
- Sophie Bouillon (born 1984), French independent journalist
- Sophie Bould (born 1982), British theatre actress
- Sophie Bradley-Auckland (born 1989), English footballer
- Sophie Bray (born 1990), English international field hockey player
- Sophie Brown (badminton) (born 1993), English badminton player
- Sophie Bruehmann (born 1995), German female acrobatic gymnast
- Sophie Byrne, Australian filmmaker
- Sophie Cadieux (born 1977), Quebec actress
- Sophie Caldwell (born 1990), American cross-country skier
- Sophie Calle (born 1953), French artist
- Sophie Campbell, American comic artist
- Sophie Carle (born 1964), Luxembourgish actress
- Sophie Carrigill (born 1994), British wheelchair basketball player
- Sophie Casey (born 1991), Australian footballer
- Sophie Choudry (born 1982), Indian singer and VJ
- Sophie Clarke (born 1989), American reality TV personality
- Sophie Colquhoun (born 1989), English actress
- Sophie Crumb (born 1981), American-French comics artist
- Sophie Dahl (born 1977), English fashion model and author
- Sophie Delila (born 1983), French singer-songwriter
- Sophie Elliott (1985–2008), New Zealand murder victim
- Sophie Ellis-Bextor (born 1979), British singer
- Sophie Evans (born 1993), British actress and singer
- Sophie Gradon (1985–2018), English model and marketing manager
- Sophie Goyette, Canadian film director and screenwriter
- Sophie Grégoire Trudeau (born 1975), Canadian model and television host, wife of Justin Trudeau
- Sophie Grigson (born 1959), British cookery writer
- Sophie Hannah (born 1971), British writer
- Sophie B. Hawkins (born 1964), American singer-songwriter
- Sophie Hecquet (1944–2012), French singer, actress and presenter
- Sophie Hopkins (born 1990), British actress
- Sophie Huet (1953–2017), French journalist
- Sophie Jaques (born 2000), Canadian ice hockey player
- Sophie Kinsella (born 1969), British writer
- Sophie Labelle (born 1988), Canadian cartoonist and transgender rights activist
- Sophie Lancaster (1986–2007), British murder victim
- Sophie Lawrence (born 1972), British actress
- Sophie Lee (born 1968), Australian actress
- Sophie Khan Levy (born 1989), English actress
- Sophie Marceau (born 1966), French actress
- Sophie McShera (born 1985), English actress
- Sophie Moleta (born 1969), New Zealand singer-songwriter
- Sophie Molineux (born 1998), Australian cricketer
- Sophie Monk (born 1979), Australian singer
- Sophie Muller (born 1962), British music video director
- Sophie Nélisse (born 2000), Canadian actress
- Sophie Okonedo (born 1968), British actress
- Sophie O'Sullivan (born 2001) Irish-Australian athlete
- Sophie Pétronin (born 1945), French-Swiss humanitarian and aid worker
- Sophie Podolski (1953–1974), Belgian poet and graphic artist
- Sophie Porley (born 1992), British actress
- Sophie Postel-Vinay, French physician and oncology researcher
- Sophie Price (born 1989), British glamour model
- Sophie Raworth (born 1968), British television presenter
- Sophie Roberts, theatre director
- Sophie Rundle (born 1988), English actress
- Sophie Scholl (1921–1943), executed German member of the WWII White Rose resistance
- Sophie Tassignon (born 1980), Belgian jazz singer-songwriter and improvisational singer
- Sophie Thompson (born 1962), British actress
- Sophie Turner (born 1996), English actress
- Sophie Vavasseur (born 1992), Irish actress
- Sophie Ward (born 1964), British actress
- Sophie Willan (born 1987/88), British comedian
- Sophie Williams (born 1991), British Olympic fencer
- Sophie Wilson (born 1957), British computer scientist
- Sophie Winkleman (born 1980), British actress
- Sophie Xeon (1986–2021), known mononymously as SOPHIE, Scottish electronic music producer
- Sophie Zelmani (born 1972), Swedish singer-songwriter
- Sophie, from the film Aftersun
- Sophie, from the Don Bluth film Anastasia
- Sophie, from the book The BFG and the films The BFG 1989 and The BFG (2016)
- Sophie, from the film Bodies Bodies Bodies
- Sophie, a minor character from the Doctor Who episode "The Lodger"
- Sophie, coworker of Rachel in season 3 of TV series Friends
- Sophie, from the television series In Treatment
- Sophie, a Belgian comics series by Jidéhem
- Sophie, from the film Mamma Mia! and its sequel
- Sophie, from the film Portrait of a Lady on Fire
- Sophie the Sapphire Fairy, from the Rainbow Magic book franchise
- Sophie of Woods Beyond, a main character in the book series The School For Good And Evil
- Sophie, from the video game Tales of Graces
- Sophie Bennett, from the DreamWorks Animation film Rise of the Guardians
- Sophie Bergmann, from the video game Fullmetal Alchemist 3: Kami o Tsugu Shōjo
- Sophie Burton, from the television series Hollyoaks
- Sophie Chapman, from the television series Peep Show
- Sophie Charalambos, from the television series Stath Lets Flats
- Sophie Devereaux, grifter in TNT's Leverage TV series
- Sophie Dumond, from the film Joker (2019 film)
- Sophie Elizabeth Foster, main character of Keeper of the Lost Cities by Shannon Messenger
- Sophie von Faninal, from the opera Der Rosenkavalier
- Sofie Fatale, from the film Kill Bill: Volume 1
- Sophie Green, from the sixth season of the television series American Horror Story
- Sophie Hatter, main character of Howl's Moving Castle
- Sophie Jones (disambiguation) § Fictional characters
- Sophie Kachinsky, from the television series 2 Broke Girls
- Sophie King, from the film Cyberbully
- Sophie Kowalsky, main character in the movie Love Me If You Dare, played by Marion Cotillard
- Sophie Lennon, from the television series The Marvelous Mrs. Maisel
- Sophie Martinez, from the television series Cory in the House
- Sophie Neuenmuller, from Atelier Sophie: The Alchemist of the Mysterious Book and its sequel
- Sophie Neveu, heroine of The Da Vinci Code
- Sophie Newman, main character of The Secrets of the Immortal Nicholas Flamel
- Sophie One and Other Sophie, from the television series The Epic Tales of Captain Underpants
- Sophie Richards, from the video game The House of the Dead
- Sophie Sanders, from Bunsen Is a Beast
- Sophie Simpson, from the television series Home and Away
- Sophie Song, from the television series Peacemaker
- Sophie Twilight, from Ms. Vampire Who Lives in My Neighborhood
- Sophie Webster, from the soap opera Coronation Street
- Sophie Zawistowska, from the novel and film Sophie's Choice