Scala or SCALA may refer to:
- Alessandra Scala (1475–1506), Italian poet and scholar
- Bartolomeo Scala (1430–1497), Italian politician, author and historian
- Delia Scala (1929–2004), Italian ballerina and actress
- Enea Scala (born 1979), Italian operatic tenor
- Flaminio Scala (1547–1624), Italian actor
- Gaetano Scala (born 1932), Italian pentathlete
- Gia Scala (1934–1972), Anglo-American actress
- Jerry Scala (1924–1993), American baseball player
- Lauren Scala (born 1982), American television reporter
- Mim Scala (born 1940), English talent agent
- Nevio Scala (born 1947), Italian soccer coach
- Salvatore Scala (1944–2008), New York mobster
- Santiago Scala (born 1991), Argentine basketball player
- Tina Scala (1935–2022), Italian-American actress
- Vincenzo Scala (fl.Tooltip floruit 1839–1893), Italian painter
- Scala!!!, a 2023 film by Ali Catterall and Jane Giles
- Scala case, a 1978 fire in Barcelona and the ensuing trial