Rocuronium bromide
Non-depolarizing neuromuscular blocker / From Wikipedia, the free encyclopedia
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Rocuronium bromide (brand names Zemuron, Esmeron) is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia to facilitate tracheal intubation by providing skeletal muscle relaxation, most commonly required for surgery or mechanical ventilation. It is used for standard endotracheal intubation, as well as for rapid sequence induction (RSI).[1]
Quick Facts Clinical data, Trade names ...
Clinical data | |
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Trade names | Esmeron, Zemuron |
Other names | [3-hydroxy-10,13-dimethyl-2-morpholin-4-yl-16-(1-prop-2-enyl-2,3,4,5-tetrahydropyrrol-1-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate |
AHFS/Drugs.com | Monograph |
Routes of administration | Intravenous |
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Pharmacokinetic data | |
Bioavailability | NA |
Protein binding | ~30% |
Metabolism | some de-acetylation |
Elimination half-life | 66–80 minutes |
Excretion | Unchanged, in bile and urine |
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ECHA InfoCard | 100.122.235 |
Chemical and physical data | |
Formula | C32H53BrN2O4 |
Molar mass | 609.690 g·mol−1 |
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