15°2′46.85″N 89°35′4.48″W Río Hondo is a municipality in the Guatemalan department of Zacapa.

Rio Hondo, Which means "Deep River" in the English language, is known for its crystal clear river.[citation needed]

Rio Hondo is mainly made up of farmlands; the likes of which include mango groves, lime groves, avocado groves, cattle, and tilapia farms.

The pueblo of Llano Verde is home to Esperanza de Vida, a large Christian humanitarian organization. Under the direction of Carlos Vargas, the Esperanza de Vida campus includes a retirement home, a nutrition center, an orphanage, a private K-12 school (Liberty College), a missions house, and St. Luke's Hospital. These centers are open to the community.

Calle 9 or Road 9 (Called "La Ruta" or "The Route" by the locals) is a major road that goes through Rio Hondo. It comes from Guatemala City and ends end Puerto Barrios.

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