Postpolypectomy coagulation syndrome
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Postpolypectomy coagulation syndrome (Postpolypectomy syndrome or PPCS) is a condition that occurs following colonoscopy with electrocautery polypectomy, which results in a burn injury to the wall of the gastrointestinal tract. The condition results in abdominal pain, fever, elevated white blood cell count and elevated serum C-reactive protein.
Quick Facts Other names, Specialty ...
Postpolypectomy coagulation syndrome | |
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Other names | Transmural burn syndrome, Postpolypectomy syndrome Coagulation syndrome |
Specialty | Gastroenterology |
Symptoms | Abdominal pain, fever |
Usual onset | 1-5 days after polypectomy |
Causes | Polypectomy during colonoscopy |
Risk factors | Hypertension, right colon polypectomy, large polyp size (>2 cm), non-polypoid lesions (laterally spreading lesions)[1] |
Differential diagnosis | Perforation |
Prevention | Antibiotic prophylaxis[2] |
Treatment | IV fluids, antibiotics, nothing by mouth |
Prognosis | Excellent |
Frequency | 1%[1] |
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