The Pony Express was a U.S. mail service that operated from April 1860 to October 1861.
Pony Express may also refer to:
- Pony express (newspapers), a dispatch service employed by newspapers prior to adoption of the telegraph
- Pony Express (roller coaster), a roller coaster at Knott's Berry Farm amusement park
- Operation Pony Express, a military operation during the Vietnam War
- Pony Express Bridge, a bridge over the Missouri River on US-36
- Pony Express Council, a scouting organization in Missouri
- Pony Express Historical Association, the not-for-profit organization that owns the historical Patee House (the headquarters of the Pony Express)
- Pony Express Museum, a transport museum in Saint Joseph, Missouri
- Pony Express Region, a region of northwestern Missouri
- Pony Express Stables, the eastern terminus of the Pony Express, now the home of the museum
- Pony Express Terminal, the western endpoint of the Pony Express