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From Wikipedia, the free encyclopedia
Plasmin-α2-antiplasmin complex (PAP) is a 1:1 irreversibly formed inactive complex of the enzyme plasmin and its inhibitor α2-antiplasmin.[1][2][3][4] It is a marker of the activity of the fibrinolytic system and a marker of net activation of fibrinolysis.[5][6]
PAP levels are increased with pregnancy[7] and by ethinylestradiol-containing combined birth control pills.[5] Conversely, levels of PAP do not appear to be affected with menopausal hormone therapy.[6] PAP levels have been reported to be elevated in men with prostate cancer.[8]
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