Komagataella
Genus of fungus used industrially and as model organism / From Wikipedia, the free encyclopedia
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Komagataella is a methylotrophic yeast within the order Saccharomycetales. It was found in the 1960s as Pichia pastoris, with its feature of using methanol as a source of carbon and energy.[2] In 1995, P. pastoris was reassigned into the sole representative of genus Komagataella, becoming Komagataella phaffii.[3] Later studies have further distinguished new species in this genus, resulting in a total of 7 recognized species.[4] It is not uncommon to see the old name still in use in the context of protein production, as of 2023;[5] in less formal use, the yeast may confusingly be referred to as pichia.
Komagataella | |
---|---|
Komagataella phaffii[1] GS115 | |
Scientific classification | |
Domain: | Eukaryota |
Kingdom: | Fungi |
Division: | Ascomycota |
Class: | Saccharomycetes |
Order: | Saccharomycetales |
Family: | Phaffomycetaceae |
Genus: | Komagataella Y. Yamada, M. Matsuda, K. Maeda & Mikata, 1995 |
Species | |
See text |
After years of study, Komagataella is widely used in biochemical research and biotech industries. With strong potential for being an expression system for protein production, as well as being a model organism for genetic study, Komagataella phaffii has become important for biological research and biotech applications.[1][5]