Phosphoramidate—hexose phosphotransferase

In enzymology, a phosphoramidate-hexose phosphotransferase (EC 2.7.1.62) is an enzyme that catalyzes the chemical reaction

phosphoramidate + hexose ${\displaystyle \rightleftharpoons }$ NH₃ + alpha-D-hexose 1-phosphate

phosphoramidate-hexose phosphotransferase
Identifiers
EC no.	2.7.1.62
CAS no.	9031-45-2
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

Thus, the two substrates of this enzyme are phosphoramidate and hexose, whereas its two products are NH₃ and alpha-D-hexose 1-phosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is phosphoramidate:hexose 1-phosphotransferase. Other names in common use include phosphoramidate-hexose transphosphorylase, and phosphoramidic-hexose transphosphorylase.