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Paraventricular nucleus of hypothalamus
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Not to be confused with Periventricular nucleus.
The paraventricular nucleus (PVN, PVA, or PVH) is a nucleus in the hypothalamus. Anatomically, it is adjacent to the third ventricle and many of its neurons project to the posterior pituitary. These projecting neurons secrete oxytocin and a smaller amount of vasopressin, otherwise the nucleus also secretes corticotropin-releasing hormone (CRH) and thyrotropin-releasing hormone (TRH).[1] CRH and TRH are secreted into the hypophyseal portal system and act on different targets neurons in the anterior pituitary. PVN is thought to mediate many diverse functions through these different hormones, including osmoregulation, appetite, and the response of the body to stress.[2]
Quick Facts Details, Identifiers ...
Paraventricular nucleus of hypothalamus | |
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![]() Human paraventricular nucleus (PVN) in this coronal section is indicated by the shaded area. Dots represent vasopressin (AVP) neurons (also seen in the supraoptic nucleus, SON). The medial surface is the 3rd ventricle (3V). | |
![]() The paraventricular hypothalamus of the mouse brain | |
Details | |
Identifiers | |
Latin | nucleus paraventricularis hypothalami |
MeSH | D010286 |
NeuroNames | 387 |
NeuroLex ID | birnlex_1407 |
TA98 | A14.1.08.909 |
TA2 | 5722 |
FMA | 62320 |
Anatomical terms of neuroanatomy |
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