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Oxidopamine
Chemical compound / From Wikipedia, the free encyclopedia
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Oxidopamine, also known as 6-hydroxydopamine (6-OHDA) or 2,4,5-trihydroxyphenethylamine, is a neurotoxic synthetic organic compound used by researchers to selectively destroy dopaminergic and noradrenergic neurons in the brain.
Quick Facts Names, Identifiers ...
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Preferred IUPAC name
5-(2-Aminoethyl)benzene-1,2,4-triol | |
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ChEBI | |
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ECHA InfoCard | 100.013.493 ![]() |
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Properties | |
C8H11NO3 | |
Molar mass | 169.18 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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The main use for oxidopamine in scientific research is to induce Parkinsonism in laboratory animals by lesioning the dopaminergic neurons of the substantia nigra pars compacta, in order to develop and test new medicines and treatments for Parkinson's disease.