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Gemtuzumab ozogamicin
Pharmaceutical drug / From Wikipedia, the free encyclopedia
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Gemtuzumab ozogamicin, sold under the brand name Mylotarg, is an antibody-drug conjugate (a drug-linked monoclonal antibody) that is used to treat acute myeloid leukemia.[6][8][9]
Quick Facts Monoclonal antibody, Type ...
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Monoclonal antibody | |
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Type | Whole antibody |
Source | Humanized (from mouse) |
Target | CD33 |
Clinical data | |
Trade names | Mylotarg |
AHFS/Drugs.com | Monograph |
MedlinePlus | a618005 |
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Routes of administration | Intravenous |
ATC code | |
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Molar mass | 151500 g·mol−1 |
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The most common side effects include infection, febrile neutropenia, decreased appetite, hyperglycemia, mucositis, hypoxia, hemorrhage, increased transaminase, diarrhea, nausea, and hypotension.[10] However, the addition of gemtuzumab ozogamicin to standard chemotherapy regimens does not increase infection rates. [11]